Furthermore, we detected severe outcomes in 46 cases of pancreatic carcinoma and all cases of pancreatic carcinoma metastatic ( n = 12), including 7 and 3 deaths, respectively, consistent with a clinical trial that reported 1 pancreatic carcinoma death, which was assessed as being probably related to semaglutide ( In addition to pancreatitis, among the moderate clinical priority signals, the most commonly reported semaglutide-related AEs were nausea (score 6), vomiting (score 6), diarrhea (score 5), constipation (score 6), and abdominal pain (score 5), and so on, which were consistent with the drug label
13 Figure 7: PIONEER 3 trial design Source: Clinical Study Report
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